Two sample MR report
RPS26_Dendritic Cell (DC) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | -0.0647947 | 0.0483026 | 0.2126445 |
| Weighted median | 11 | -0.0440734 | 0.0088965 | 0.0000007 |
| Inverse variance weighted | 11 | -0.0488883 | 0.0066147 | 0.0000000 |
| Simple mode | 11 | -0.0387449 | 0.0121615 | 0.0097219 |
| Weighted mode | 11 | -0.0417231 | 0.0113657 | 0.0043103 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.232093 | 9 | 0.4161318 |
| Inverse variance weighted | 9.345514 | 10 | 0.4996568 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0096704 | 0.0290822 | 0.7471103 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0013063 | 1e-07 | TRUE | 0.0006272 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
